Job Description

We are on a quest for cures and are committed to be the world's premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines.

We are seeking an exceptional Scientist in the Boston Discovery Biologics group, with the primary responsibility to execute cell-based binding and functional assays. The qualified candidate will be a scientist with core capabilities in cell culture, automation and high-throughput cell-based assay execution and statistical data analysis in the quest to discover innovative large molecule therapeutics. They should have deep expertise in cell technologies, dose-response relationship and using proper statistical tools for data analysis and interpretation. They will also serve as the assay development and screening representative on project teams, driving protein therapeutics programs from concept through hit identification and lead optimization.The ideal candidate will have first-hand knowledge of aseptic technique in cell culture including subculturing and cryopreservation of cells, flow cytometry sample preparation, reporter gene assay configuration, data acquisition, analysis, and reporting.

They will work to support the department's efforts to recruit diverse and highly skilled key talent to the organization and be a champion for diversity and inclusion. We recognize that the diversity in our team is our strength, and we are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of researchers to drive our core mission.

What you will do:

• Contribute to the binding and functional characterization of therapeutic molecules via cellular and/or biochemical assays.

• Implement assay automation to screen drug candidates in early discovery pipelines.

• Plan, design, execute and troubleshoot in vitro pharmacological experiments to support and advance drug discovery programs.

• Maintain timely, accurate laboratory records of activities & comply with good documentation practices.

• Effectively collaborate with integrated teams in a matrix organization setting to facilitate the conduct of studies and to the success of discovery programs.

What you will need to be successful in this role:

Qualifications & Experience

• M.S. in pharmacology, immunology, biotechnology or biology, with 1+ years or B.S. with 3+ years of relevant in vitro, cell-based assay experience, preferably in a pharmaceutical/ biotechnology setting. Highly relevant lab experience through degree program can be considered

• Excellent communication and collaboration skills

Required skills:

• Hands-on experience with mammalian cell culture, flow cytometry and related data analysis.

• Working knowledge using standard data analysis tools such as FlowJo, Graph Pad Prism and Microsoft programs.

• Familiarity with automated liquid handling systems, robotics, and high-throughput cell-based assays screening formats.

• Ability to multi-task with highly analytical mind, attention to details, and organizational skills are critical.

• Excellent written and interpersonal communication skills and the ability to collate the results and make a presentation to the stakeholders.

• The ability to work independently, as well as collaboratively with peers within and across departments is expected.

• Champion for diverse and inclusive culture

Preferred skills:

• Experience in assay development in a wide range of cellular and biochemical assays such as reporter gene assays, Ab internalization assay, enzymatic activity assays, etc.

• Experience with developing high throughput methods into workflows (e.g. Hamilton and/or Agilent Bravo automated liquid handling platform, Thermo Scientific Momentum workflow scheduling software, etc.)

• ELISA and other immunological assay skills are desired.

Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At our company, we're inventing for life.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

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We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Job Posting End Date:

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:09/18/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R311432