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GSK
MES Engineer
GSK
King of Prussia, PA
Jun 3, 2025
Full Job Description

The purpose of the MES Engineer is to provide intermediate level technical support of manufacturing execution systems (Syncade) in a biopharmaceutical manufacturing facility. Provide technical backstop support of daily operations and drive continuous improvement and scaling of the existing footprint.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Provide support and technical subject matter expertise to the site’s deployments of Emerson Syncade (manufacturing execution system). Ensure the reliable performance and continuous improvement/optimization the MES footprint.
    • Recipe authoring, Equipment, Material, Order Management, software development and testing.
    • Troubleshoot plant floor MES execution and integration issues.
    • Change Control, Validation, and Qualification Management of system changes.
    • Compliance and inspection readiness of MES.
  • Maintain and upkeep Syncade through administration and break/fix support of related systems, networks, integrations, databases, and accounts.
    • Able to query and assess the Syncade data warehouse (SQL).
    • Perform hotfix upgrades in Syncade. Includes assessing change impact, provisioning in kind, performing the upgrade, testing, and hypercare.
    • Understand SC Consumer, Business Integrator, Event Monitor, OPC Client/Server, Infobatch Report Design and Integration, and troubleshoot performance and function of each component as it relates to the complete MES solution design (including other integrated systems and operational context).
  • Understand the flow of data among business and operational technology systems, with a focus on Syncade, including technical nuances as well as operational context to make sense of the end to end flow.
  • Improve Department performance and posture through continuous improvement (e.g. procedural, way of working, capability, etc.).
  • Contribute to further scaling of Syncade by providing key input to solution design as well as project/executional design. Contribute to related capital investments. Rationalize performance and investment with business impact.
  • Collaborate with Operations and building stakeholders throughout the software or system development lifecycle: gather system/end user requirements; complete design, implementation, and testing/validation of changes; document changes; maintain and monitor the system; ensure end user readiness.
  • Work in a way that models respect for safety and EHS, quality compliance, data integrity, and engineering standards.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • BS/BA in engineering, computer science, IT, or equivalent technical discipline
  • OR 4+ years of MES experience in Life Sciences in lieu education
  • 3+ years engineering, troubleshooting, and solutions design of Emerson Syncade , Körber/Werum PAS-X, Siemens Opcenter Execution Pharma (Simatic EBR), POMS, Rockwell PharmaSuite, or other Life Sciences focuse MES systems.
  • 2+ years working in a GMP manufacturing setting

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Windows Server Administration including
    • Active Directory and Security Models
    • TCP/IP Networking, Routing, Ports and Firewalls
    • Internet Information Services (IIS), Secure Website Administration, ASP
    • Remote Desktop Services
    • Event Monitoring, Services, Registry, Scripting Technologies such as vbscript
  • Database Administration and Design (SQL)
  • XML/XSL. Web services.
  • Emerson SC Consumer, Business Integrator, and Event Monitor.
  • SAP PPM Understanding, Use, and Integration
  • OPC Client/Server Architecture and Troubleshooting
  • S95/S88 Batch Execution Systems such as DeltaV Campaign Manager/Batch Executive/Batch Historian
  • Informetric Systems Infobatch. XSLT.
  • Able to function within team based organization.

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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Job Category:
Engineering
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MES Engineer
GSK
King of Prussia, PA
Jun 3, 2025
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