1. Choose your Affinity Group

* Equal Opportunity / Affirmative Action

We serve Equal Opportunity Employers and are an Equal Opportunity Employer. The Professional Diversity Network has separate professional networking sites for different affinities, and in selecting the groups you identify with, you will be joined with those networks.

Note: Providing this information is strictly voluntary - you will not be penalized or subjected to adverse treatment. If you choose not to provide this information, simply select "Choose not to identify."

2. Choose Method
Sign in with LinkedIn
Sign in with Facebook

Tell us about yourself

Associate Director, Clinical Biomarkers
at Vertex Pharmaceuticals Inc (US)
Boston, MA

Associate Director, Clinical Biomarkers
at Vertex Pharmaceuticals Inc (US)
Boston, MA

Save or bookmark jobs as you go and access them anytime later with your account.



We are seeking a highly motivated scientist to act as a Clinical Biomarker Lead, working in a dynamic, cross- functional environment within the clinical development team to implement biomarker strategies for Vertex clinical assets. This position will report directly to the Head of Clinical Biomarkers.

Key Responsibilities:

  • Responsible for developing the clinical biomarker strategy for programs and implementing the biomarker plan during clinical development.
  • Collaborate with Research and Translational Medicine on development of translational biomarker plans.
  • Collaborate with Clinical Study Teams and colleagues in Translational Medicine and Clinical Development to ensure appropriate inclusion of Clinical Biomarkers in clinical studies, including study design.
  • Coordinate with Clinical Pharmacology, Biostatistics and Modeling & Simulation to support quantitative pharmacological approaches during clinical development.
  • Work with Project Management to ensure the development of Companion Diagnostics in parallel to drug development as appropriate.
  • Serve as a key member of project teams, providing expert input to teams and guiding clinical development of novel biomarkers.
  • Manage work with CRO and/or collaborate with colleagues from Biomarker Labs to ensure fit-for-purpose validation of clinical biomarker assays prior to implementation.
  • Partner with colleagues across the clinical and research organizations to foster an end-to-end view of drug development, always focusing on improving patient care.
  • Identify and lead opportunities for biomarker-focused external collaboration

Minimum Qualifications :

  • Demonstrated experience with design, execution and analysis of clinical biomarkers of target engagement, safety, pharmacodynamics, and efficacy.
  • Innovative and able to think creatively with a strong drive toward decision making.
  • Effective at building alliances across functions, based on end-to-end drug development experience.
  • Excellent interpersonal and communication skills, able to drive global collaborations across a matrixed organization.
Preferred Qualifications:
  • Preferably a PhD and/or MD with clinical biomarker development experience (at least 3+ years post-degree industry experience in the development and execution of Clinical Biomarker strategies).
  • Experience in Neuroscience and Pain therapeutic area is desirable but not required.

Similar Jobs

See All »

Other Jobs at Vertex Pharmaceuticals...

See All »