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Senior Director, Biology (Drug Discovery)
at Vertex Pharmaceuticals Inc (US)
San Diego, CA

Senior Director, Biology (Drug Discovery)
at Vertex Pharmaceuticals Inc (US)
San Diego, CA

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Description

Vertex Pharmaceuticals Incorporated is seeking an exceptional scientific leader to drive the development and incorporation of human disease models and assays into drug discovery programs. The individual will lead a department of approximately 15 staff who are responsible for the design, development and execution of in vitro and in vivo assays to support progression and optimization of human therapeutics. This includes design and execution of pharmacology assays to determine drug potency, efficacy and mechanism of action. The ideal candidate must be able to think strategically and possess leadership abilities to inspire, direct and manage scientists, and coordinate activities across multiple drug discovery programs and departments. The Sr. Director of Biology will serve as a member of the research leadership team in our San Diego site and will be expected to influence the site's direction and lead cross-site or cross-departmental projects and initiatives. In addition, the candidate must work well in a matrix organization, make clear decisions in a fast-paced drug discovery environment and be highly proficient in both verbal and written communication to audiences with diverse scientific, professional and drug discovery backgrounds.

Minimum Qualifications:

  • Ph.D. in Molecular Biology, Cell Biology, Systems Biology, Pharmacology or related field with, relevant -post-doctoral employment experience
  • 12+ years of drug discovery experience with demonstrated excellence in early stage drug discovery and development
  • Strong strategic scientific and technical leadership in the design, execution, analysis and interpretation of a broad range of ion channel pharmacology/electrophysiology assays to drive compound progression and elucidate mechanism of action
  • Understanding of classical pharmacological principles and drug discovery process, in order to support assessment of potency, efficacy and contribute to predictions of human efficacy
  • Ability to critically analyze and interpret data, and effectively document and communicate results and recommend next steps to diverse audiences
  • Ability to propose and/or support external collaborations leading to innovative solutions
  • Successful track record in managing functional or cross-functional research groups, including Ph.D. Scientists and Research Associates

Preferred Qualifications:

  • Experience leading groups in a pharmaceutical or biotechnology setting
  • Assay development expertise, including biochemical and cell-based assays
  • Evidence of development of innovative translational in vitro and/or in vivo models that predict human efficacy

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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