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Senior Director - Project Portfolio Management for Enterprise Systems
at Vertex Pharmaceuticals Inc (US)
Boston, MA

Senior Director - Project Portfolio Management for Enterprise Systems
at Vertex Pharmaceuticals Inc (US)
Boston, MA

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The Senior Director, Project Portfolio Management will be responsible for overseeing and managing the IT project portfolio for the Enterprise Applications and Analytics function. This is a critical role, in place to ensure that this cross-functional portfolio of IT initiatives has been prioritized appropriately and is aligned to business strategies, goals, and objectives. The Senior Director will verify that all projects in the portfolio are resourced and funded appropriately, risks and issues are properly mitigated, and proper governance/ communication procedures are in place. The Senior Director will also be responsible for directly managing larger, strategic initiatives to ensure successful delivery.


  • Partner with the GIS Program Management Office (PMO) to establish improved processes, tools and templates in order to effectively prioritize and manage our Enterprise Applications and Analytics project portfolio
  • Direct and oversee successful project delivery across the portfolio with clear accountability and transparency across the teams and business stakeholders, including success criteria, risks/issues, budgets and resources
  • Build strong relationships with peers and colleagues across the GIS organization, and with key business partners, in order to plan and execute the project portfolio
  • Clearly communicate and present project portfolio strategies and updates to senior leaders, business partners, and the GIS Leadership Team
  • Manage large and complex strategic initiatives and programs effectively and efficiently
  • Provide ongoing support and guidance for other project managers across the team, including expertise for different project methodologies (Agile, Scrum, Waterfall) and regulatory complexities (GxP, Sarbanes-Oxley)
  • Recruit, manage, and coach additional project managers as the team expands in support of Vertex and GIS' strategies and growth


  • Deep expertise and background with IT project and portfolio management concepts and frameworks (e.g. SDLC, Agile)
  • Demonstrated proficiency in managing large, complex projects
  • Experience leading organizational change management efforts for enterprise programs
  • Very strong communication, interpersonal, and collaborative skills
  • Ability to effectively facilitate and manage cross-functional meetings and discussions
  • Excellent presentation skills and ability to clearly and succinctly express ideas
  • Proven capabilities in building and leading high-performing project teams


  • B.S. and 12+ years relevant work experience
  • Biotech or pharmaceutical industry experience
  • Experience with general and administrative, manufacturing and supply chain business functions and systems
  • Hands on experience with the Agile project methodology
  • Direct experience in complying with GxP and/or Sarbanes-Oxley (SOX) regulations

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