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Senior Scientist I, Discovery Biology
at Vertex Pharmaceuticals
Watertown, MA

Senior Scientist I, Discovery Biology
at Vertex Pharmaceuticals
Watertown, MA

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In June 2019, Vertex announced the establishment of a new research site in the Boston area where research, development, and clinical manufacturing for cell and genetic therapies will be primarily based. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat-and even cure-several of the diseases Vertex is focused on, including sickle cell disease, Duchenne muscular dystrophy and type 1 diabetes. Further investment in a research site specifically designed to advance these programs will be key to Vertex's continued and sustained leadership in these exciting approaches. At Vertex Cell and Genetic Therapies (VCGT) our research teams will bring together the best biology, technologies and enhanced manufacturing capabilities to ensure we bring these cutting-edge transformative therapies to patients as quickly as possible.


  • Perform studies to progress our portfolio of CRISPR-based gene editing therapies.
  • Assume project responsibilities and effectively present updates to the senior leadership team.
  • Oversee study design and execution, data analysis and report writing.
  • Effectively collaborate with a fully integrated team to facilitate the success of projects.


  • PhD or equivalent in a relevant biological discipline and 3+ years of pharmaceutical industry experience.
  • Deep understanding of drug discovery, gene therapy, molecular pharmacology and drug development.
  • Working experience with AAV vectors and/or CRISPR/Cas9 system.
  • Familiarity with the preclinical regulatory requirements for gene therapy/editing programs.
  • Excellent communication skills with the proven ability to work effectively as a member of a multidisciplinary team.


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